Spinning out of the original Ash mini-series, 22 Brides expands the shared Event Universe. This series introduces us to the full band of Brides, including the first appearance of Painkiller Jane, as well as the Brides man-servants Joseph and James (who look suspiciously like a couple of comic book creators).
The first two issues of the series were printed on a lower quality newsprint stock paper while the second two issues were upgraded to a thin glossy stock paper (similar to Ash #6).
22 Brides next appear in Ash/22 Brides #1-2. Painkiller Jane next appears in Painkiller Jane vs the Darkness: Stripper.