"The Greatest Responsibility, Part One: Crossroads"
Continues in Spider-Man #63.
First appearance of Doctor Octopus (Carolyn Trainer), later known as Lady Octopus.
Peter and Mary Jane vist Dr. Trainer to find out if there any cause for alarm, being as Peter is really a clone. The new Dr. Octopus is working on a device that will simulate reality illusions that could devastate the world. In the end we find out what is the strained relationship that is between her and Dr. Trainer. (Doctor Octopus in the comic is a female that goes by the same name and has the same tentacles as Otto Octavius)
Includes two Marvel OverPower game cards.