I think I liked Deadpool better without Hydra Bob. When he was first introduced in the previous series, I thought he was a nice touch. Now though, he just sort of bugs me. I enjoyed his triple cross in this issue; it was clever, but he just seems to get in the way of the story (and not in the intentional way that Way meant it - that was way too many ways there - I'll stop.)
Some good humour, nice references and interesting breaking of traditional comic book writing rules. Medina is a good artist. His lines might be a little too clean for this series though.
Hopefully Wade's upcoming confrontation with the Thunderbolts will put Deadpool back on the right track. It has been a few issues now that I have been whining about what a good Deadpool issue should look like. This would be a good place to start exploring this side of the character.