This issue sees Deadpool finish his ongoing battle with Bullseye. And in the long run, the world's deadlisest assassin can't even hold a candle to the merc with a mouth.
Deadpool doesn't just win, Bullseye surrenders. And then pays Wade a boatload of money to disappear so that Osborn thinks he finished the job he was assigned. This issue secures it for me. I think that Deadpool could beat anyone in the Marvel U.! Doctor Strange, Sentry, Leach, bring them on!
I didn't really understand the ending. But hey, it's Deadpool, why should I?