This issue takes place before Amazing Spider-Man (1963) #654.
*Ever wonder how X-Factor manages to operate out in the open in a New York City where superhero-hating J. Jonah Jameson is the mayor? Well, here's where you find out, as jolly JJJ thrusts NYC's premiere detective agency into the midst of a murder investigation where the trail may lead them straight to...Jonah himself? Guest-starring the ever-amazing Spider-Man and the Black Cat! *Source: marvel.com