By the end of the 1991 Aliens vs Predator series, the only human survivor, Machiko Noguchi, has been completely separated from human contact for over 2 yrs, & accepted Albeit Grudgingly into a Preadator hunting clan. The action in the previous series all took place on Machiko's adopted home world of Ryushi, a sparsely poplulated colony planet and a planet seeded with alien eggs to produce "sport" for Predator hunting trips. Machiko had prover her fighting skills against the Aliens alongside Broken Tusk, and the Predator's dying gift to her was a brand burnt with Alien blood into her forehead.
As War begins, Machiko is traveling from world to world with the Predator clan, led by the one she calls "Topknot", seeding new hunting areas with alien eggs. It's a constant struggle for her to learn the ways of the Predators & maintiain her status within the clan. A Predator generally does that by proving to be the fiercest hunter around...